Potential New Vaccine Blocks Fentanyl ‘High’ and Could Help Fight Opioid Crisis, Say Researchers

Published on August 31, 2024

More than 81,000 people died in 2023 due to synthetic opioid overdose, according to provisional data from the U.S. Centers for Disease Control and Prevention. Almost 75,000 of those deaths were due to illicit fentanyl, a synthetic opioid. In comparison, the number of U.S. troops who died during the entire 20-year Vietnam war was 58,220, according to the National Archives. To help address the opioid crisis, doctors such as Dr. Colin Haile of the University of Houston’s Drug Discovery Institute are hoping to block fentanyl’s ability to enter the brain, eliminating the drug’s euphoric effect, or “high.” Early results suggest that their method, a vaccine, not only accomplishes that goal but also eliminates fentanyl’s lethality in the vaccinated....

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