Paxlovid Doesn’t Work in Many Vaccinated People: Pfizer Study

Published on April 4, 2024

Pfizer’s COVID-19 drug did not work for many vaccinated people, according to a new paper from the company’s scientists. There was not a statistically significant difference between Paxlovid and placebo recipients in terms of time to alleviation of symptoms, the scientists reported in the new paper. The paper, published by the New England Journal of Medicine, describes the results of a company-funded phase 2-3 trial of the drug, which is also known as nirmatrelvir. The trial enrolled adults who tested positive for COVID-19, showed at least one COVID-19 symptom, had previously received a COVID-19 vaccine, and had at least one risk factor, such as being a cigarette smoker, for severe COVID-19. Participants were randomized from Aug. 25, 2021, to July 25, 2022....

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