Half-Dose of COVID-19 Booster Just as Effective as a Full Dose: Study

Reducing the dose of a Pfizer COVID-19 booster vaccine can elicit a comparable immune response in adults compared to a full dose with fewer side effects, new research has found. Led by the Murdoch Institute and the National Centre for Communicable Diseases in Mongolia, the study involved 601 participants over 18 years old from Mongolia, and is the first to assess and compare widely used COVID-19 vaccines in low- and middle-income countries. The study focused on adults who had previously received AstraZeneca or Sinopharm COVID-19 shots, finding that a half dose of the Pfizer booster produced a non-inferior immune response. Murdoch Institute’s Professor Kim Mulholland said reduced doses would make booster programs more cost-effective....